Where i can download defalut ASUS laptop software - Computers ...

what fogman said,

sometimes companies drop support for very old machines, it isnt very likely given the age of yours,
should that be the case you can search for the technical specifications and search for the components one by one, they are usually made by other vendors that carry support for far longer.
_________________
//through chaos comes complexity//

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Source: http://www.wrongplanet.net/postt212296.html

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Obama: Romney trying 'to cloud' abortion stance (The Arizona Republic)

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Republicans in position to extend advantage among governors (reuters)

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Enzyme triggers cell death in heart attack

ScienceDaily (Oct. 11, 2012) ? University of Iowa researchers have previously shown that an enzyme called CaM kinase II plays a pivotal role in the death of heart cells following a heart attack or other conditions that damage or stress heart muscle. Loss of beating heart cells is generally permanent and leads to heart failure, a serious, debilitating condition that affects 5.8 million people in the United States.

Now the UI team, led by Mark Anderson, M.D., Ph.D., professor and head of internal medicine at the UI Carver College of Medicine, has honed in on how CaM kinase II triggers heart cell death following heart damage, showing that the action takes place in the cells' energy-producing mitochondria. In animal tests, the team reports that blocking the enzyme can prevent heart cells from dying, and protects the animals from heart failure.

Mitochondrial are the cells' batteries, generating the energy cells need to work. In heart cells, energy produced by these small cellular components fuels each heartbeat. However, when the heart is stressed, for example during a heart attack, the mitochondria become leaky and non-functional, which triggers cell death and heart failure.

"We found that activity of the CaM kinase II enzyme in mitochondria promotes cell death when the heart is stressed," says Mei-ling Joiner, Ph.D., UI assistant professor of internal medicine and lead author of the study, which was published online Oct. 10 in the journal Nature. "The findings might help us advance treatment of heart diseases and reduce mortality after a heart attack."

The new study shows that activated CaM kinase II promotes leakiness of mitochondria and increases heart muscle damage by allowing too much calcium to enter mitochondria. Specifically, the UI team found that CaM kinase II regulates calcium entry into mitochondria by modifying a special mitochondrial calcium channel. Too much enzyme activity increased the amount of calcium flowing into mitochondria, and this calcium overload triggers cell death.

Using genetically modified mice, the team also showed that inhibiting CaM kinase II activity in mitochondria prevented the calcium overloading, reduced mitochondrial disruption, and protected the mice from heart cell death during heart attack.

These findings provide insight into molecular mechanisms for mitochondrial function and suggest that inhibiting the CaM kinase II enzyme in mitochondria could lead to new and more effective therapies for common forms of heart disease.

"Because mitochondria also play important roles in other diseases in brain and skeletal muscle, for example, our findings could also have broad implications for understanding and treating non-cardiac diseases," says Anderson, who also is director of the UI Cardiovascular Research Center.

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Story Source:

The above story is reprinted from materials provided by University of Iowa Health Care, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Mei-ling A. Joiner, Olha M. Koval, Jingdong Li, B. Julie He, Chantal Allamargot, Zhan Gao, Elizabeth D. Luczak, Duane D. Hall, Brian D. Fink, Biyi Chen, Jinying Yang, Steven A. Moore, Thomas D. Scholz, Stefan Strack, Peter J. Mohler, William I. Sivitz, Long-Sheng Song, Mark E. Anderson. CaMKII determines mitochondrial stress responses in heart. Nature, 2012; DOI: 10.1038/nature11444

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/5IbQTKgbIVw/121011162154.htm

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Pioneer anomaly solved? Interstellar travelers of the future may be helped by physicist's calculations

ScienceDaily (Oct. 9, 2012) ? Interstellar travel will depend upon extremely precise measurements of every factor involved in the mission. The knowledge of those factors may be improved by the solution a University of Missouri researcher found to a puzzle that has stumped astrophysicists for decades.

"The Pioneer spacecraft, two probes launched into space in the early 70s, seemed to violate the Newtonian law of gravity by decelerating anomalously as they traveled, but there was nothing in physics to explain why this happened," said Sergei Kopeikin, professor of physics and astronomy in MU's College of Arts and Science. "My study suggests that this so-called Pioneer anomaly was not anything strange. The confusion can be explained by the effect of the expansion of the universe on the movement of photons that make up light and radio waves."

Beams of radio waves were sent to and bounced off the Pioneer spacecraft to measure the probes' movement. The time it took for the photons to complete a round trip was used to calculate the spacecrafts' distance and speed. Kopeikin's research suggests that the photons move faster than expected from the Newtonian theory thus causing the appearance of deceleration, though the craft were actually traveling at the correct speed predicted by the theory. The universe is constantly expanding and this alters the Earth-based observations of the photons bouncing off the spacecraft, causing the Pioneer probes to appear to slow down.

"Previous research has focused on mechanical explanations for the Pioneer anomaly, such as the recoil of heat from the craft's electrical generators pushing the craft backwards," Kopeikin said. "However that only explains 15 to 20 percent of the observed deceleration, whereas it is the equation for photons that explains the remaining 80-85 percent."

Physicists must be careful when dealing with propagation of light in the presence of the expansion of space, noted Kopeikin, since it is affected by forces that are irrelevant in other equations. For example, the expansion of the universe affects photons, but doesn't influence the motion of planets and electrons in atoms.

"Having accurate measurements of the physical parameters of the universe help us form a basis to make plans for interstellar exploration," Kopeikin said. "Discerning the effect of the expansion of the universe on light is important to the fundamental understanding of space and time. The present study is part of a larger on-going research project that may influence the future of physics."

The study "Celestial ephemerides in an expanding universe," was published in the journal Physical Review D.

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Story Source:

The above story is reprinted from materials provided by University of Missouri-Columbia.

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---

Journal References:

1. Sergei Kopeikin. Celestial ephemerides in an expanding universe. Physical Review D, 2012; 86 (6) DOI: 10.1103/PhysRevD.86.064004
2. Sergei Kopeikin. Celestial ephemerides in an expanding universe. Physical Review D, 2012; 86 (6) DOI: 10.1103/PhysRevD.86.064004

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/7OFVAEIbI1o/121009161103.htm

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Simplify Your Business Through Search Engine Marketing Tips - PDF

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Tips

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the lame ROI figures would indicate, one must come to grips having a sobering conclusion. If
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---

Source: http://pdfcast.org/pdf/simplify-your-business-through-search-engine-marketing-tips

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India faces Twitter backlash over Internet clampdown

The backlash came as New Delhi turned up the heat on Twitter, threatening "appropriate and suitable action" if it failed to remove the accounts as soon as possible. Several Indian newspapers said this could mean a total ban on access to Twitter in India but government officials would not confirm to Reuters that such a drastic step was being considered.

There was no immediate response from Twitter, which does not have an office in India. There are about 16 million Twitter users in the South Asian country.

The government has found itself on the defensive this week over what critics see as a clumsy clampdown on social media websites - including Google, YouTube and Facebook - that has raised questions about freedom of information in the world's largest democracy.

"Dear GOI (Government of India), Keep your Hands Off My Internet. Else face protest" tweeted one user, @Old_Monk60.

India blocked access to more than 300 Web pages after threatening mobile phone text messages and doctored website images fuelled rumors that Muslims, a large minority in the predominantly Hindu country, were planning revenge attacks for violence in the northeastern state of Assam, where 80 people have been killed and 300,000 have been displaced since July.

Fearing for their lives, tens of thousands of migrants fled Mumbai, Bangalore and other cities last week. The exodus highlighted underlying tensions in a country with a history of ethnic and religious violence.

According to documents obtained by Reuters, the government has targeted Indian journalists, Britain's Daily Telegraph, the Australian Broadcasting Corporation and Al Jazeera television in its clampdown on Internet postings it says could inflame communal tensions.

The directives to Internet service providers listed dozens of YouTube, Facebook and Twitter pages. A random sampling of the YouTube postings revealed genuine news footage spliced together with fear-mongering propaganda.

INDIAN JOURNALISTS TARGETED

The government says Google and Facebook have largely cooperated while Twitter has been much slower to respond.

"Every company, whether it's an entertainment company, or a construction company, or a social media company, has to operate within the laws of the given country," said Sachin Pilot, minister of state in the Ministry of Communications.

Twitter has been instructed to remove 28 pages containing "objectionable content", an interior ministry official said.

"If they do not remove the pages, the Indian government will take appropriate and suitable action," he added.

The government has ordered Internet service providers to block the Twitter accounts of veteran journalist Kanchan Gupta and television anchor Shiv Aroor. Some appeared to have begun complying with the order on Thursday as Twitter users reported difficulties in accessing their pages.

"It is a political decision, because of my criticism of the government," said Gupta, who was an official in the previous government led by the Hindu nationalist Bharatiya Janata Party.

The government's actions triggered a storm of criticism from Twitter users, with the hashtags #Emergency2012 and #GOIBlocks among the top trending topics on Twitter in India on Thursday. Some compared the situation with the state of emergency imposed by the government in 1975, when some journalists were jailed.

The Centre for Internet and Society, which analyzed the 300 banning orders, found that they contained "numerous mistakes and inconsistencies". Some of the banned websites belonged to people trying to debunk the rumors, for example, it said.

"This isn't about political censorship. This is about the government not knowing how to do online regulation properly," said CIS program manager Pranesh Prakash.

India's parliament last year passed a law that obliges Internet companies to remove a range of objectionable content when requested to do so, a move criticized at the time by rights groups and social media companies.

(Additional reporting by Ross Colvin, Annie Banerji and David Lalmalsawma; Writing by Ross Colvin; Editing by John Chalmers and Andrew Osborn)

Source: http://www.ibtimes.com/articles/20120823/india-faces-twitter-backlash-over-internet-clampdown.htm

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